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BMCBI
2006
13 years 8 months ago
2006
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
BMCBI
2006
13 years 8 months ago
2006
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
BMCBI
2006
13 years 8 months ago
2006
Background: Microarray technology has become a widely accepted and standardized tool in biology. The first microarray data analysis programs were developed to support pair-wise co...
BMCBI
2006
13 years 8 months ago
2006
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
BMCBI
2006
13 years 8 months ago
2006
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...