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BMCBI
2006
91views more  BMCBI 2006»
13 years 7 months ago
Cheminformatics methods for novel nanopore analysis of HIV DNA termini
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
Stephen Winters-Hilt, Matthew Landry, Mark Akeson,...
BMCBI
2006
103views more  BMCBI 2006»
13 years 7 months ago
Meta-All: a system for managing metabolic pathway information
Background: Many attempts are being made to understand biological subjects at a systems level. A major resource for these approaches are biological databases, storing manifold inf...
Stephan Weise, Ivo Grosse, Christian Klukas, Dirk ...
IJAR
2008
118views more  IJAR 2008»
13 years 7 months ago
Dynamic multiagent probabilistic inference
Cooperative multiagent probabilistic inference can be applied in areas such as building surveillance and complex system diagnosis to reason about the states of the distributed unc...
Xiangdong An, Yang Xiang, Nick Cercone
BMCBI
2007
106views more  BMCBI 2007»
13 years 7 months ago
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive as
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Raja Jothi, Teresa M. Przytycka, L. Aravind
BMCBI
2007
153views more  BMCBI 2007»
13 years 7 months ago
Analysis of nanopore detector measurements using Machine-Learning methods, with application to single-molecule kinetic analysis
Background: A nanopore detector has a nanometer-scale trans-membrane channel across which a potential difference is established, resulting in an ionic current through the channel ...
Matthew Landry, Stephen Winters-Hilt
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