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APBC
2003
138views Bioinformatics» more  APBC 2003»
13 years 9 months ago
A New Approach to Protein Structure and Function Analysis Using Semi-structured Databases
The development of high-throughput genome sequencing and protein structure determination techniques have provided researchers with a wealth of biological data. Integrated analysis...
William M. Shui, Raymond K. Wong, Stephen C. Graha...
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
TOPSAN: a collaborative annotation environment for structural genomics
Background: Many protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositi...
Dana Weekes, S. Sri Krishna, Constantina Bakolitsa...
BMCBI
2007
227views more  BMCBI 2007»
13 years 7 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
CORR
2011
Springer
243views Education» more  CORR 2011»
13 years 2 months ago
Localization from Incomplete Noisy Distance Measurements
—We consider the problem of positioning a cloud of points in the Euclidean space Rd , from noisy measurements of a subset of pairwise distances. This task has applications in var...
Adel Javanmard, Andrea Montanari
ISMB
2000
13 years 9 months ago
Towards a Systematics for Protein Subcellular Location: Quantitative Description of Protein Localization Patterns and Automated
Determination of the functions of all expressed proteins represents one of the major upcoming challenges in computational molecular biology. Since subcellular location plays a cru...
Robert F. Murphy, Michael V. Boland, Meel Velliste