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    BMCBI
    2007
    265views more  BMCBI 2007»
    Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
    13 years 9 months ago
    Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
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    Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
    Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
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    BMCBI
    2010
    70views more  BMCBI 2010»
    The Text-mining based PubChem Bioassay neighboring analysis
    13 years 9 months ago
    The Text-mining based PubChem Bioassay neighboring analysis
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    Background: In recent years, the number of High Throughput Screening (HTS) assays deposited in PubChem has grown quickly. As a result, the volume of both the structured informatio...
    Lianyi Han, Tugba O. Suzek, Yanli Wang, Steve H. B...
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    BMCBI
    2010
    96views more  BMCBI 2010»
    OpenChrom: a cross-platform open source software for the mass spectrometric analysis of chromatographic data
    13 years 9 months ago
    OpenChrom: a cross-platform open source software for the mass spectrometric analysis of chromatographic data
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    Background: Today, data evaluation has become a bottleneck in chromatographic science. Analytical instruments equipped with automated samplers yield large amounts of measurement d...
    Philip Wenig, Juergen Odermatt
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    BMCBI
    2007
    169views more  BMCBI 2007»
    Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
    13 years 9 months ago
    Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
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    Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
    Abdallah Sayyed-Ahmad, Kagan Tuncay, Peter J. Orto...
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    BMCBI
    2007
    134views more  BMCBI 2007»
    Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
    13 years 9 months ago
    Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
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    Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
    Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
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