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BMCBI
2007
169views more  BMCBI 2007»
13 years 7 months ago
Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
Abdallah Sayyed-Ahmad, Kagan Tuncay, Peter J. Orto...
BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shoc
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
Ester Vilaprinyó, Rui Alves, Albert Sorriba...
KDD
2008
ACM
206views Data Mining» more  KDD 2008»
14 years 8 months ago
Identifying biologically relevant genes via multiple heterogeneous data sources
Selection of genes that are differentially expressed and critical to a particular biological process has been a major challenge in post-array analysis. Recent development in bioin...
Zheng Zhao, Jiangxin Wang, Huan Liu, Jieping Ye, Y...
CORR
2010
Springer
111views Education» more  CORR 2010»
13 years 5 months ago
Analysis Of Cancer Omics Data In A Semantic Web Framework
Our work concerns the elucidation of the cancer (epi)genome, transcriptome and proteome to better understand the complex interplay between a cancer cell's molecular state and ...
Matthew Holford, James P. McCusker, Kei-Hoi Cheung...
BMCBI
2006
142views more  BMCBI 2006»
13 years 7 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins