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BMCBI
2010
96views more  BMCBI 2010»
13 years 7 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
RECOMB
2003
Springer
14 years 8 months ago
Whole-genome comparative annotation and regulatory motif discovery in multiple yeast species
In [13] we reported the genome sequences of S. paradoxus, S. mikatae and S. bayanus and compared these three yeast species to their close relative, S. cerevisiae. Genome-wide comp...
Manolis Kamvysselis, Nick Patterson, Bruce Birren,...
BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
Gene set enrichment analysis for non-monotone association and multiple experimental categories
Background: Recently, microarray data analyses using functional pathway information, e.g., gene set enrichment analysis (GSEA) and significance analysis of function and expression...
Rongheng Lin, Shuangshuang Dai, Richard D. Irwin, ...
BMCBI
2010
216views more  BMCBI 2010»
13 years 2 months ago
Bayesian Inference of the Number of Factors in Gene-Expression Analysis: Application to Human Virus Challenge Studies
Background: Nonparametric Bayesian techniques have been developed recently to extend the sophistication of factor models, allowing one to infer the number of appropriate factors f...
Bo Chen, Minhua Chen, John William Paisley, Aimee ...
BMCBI
2007
97views more  BMCBI 2007»
13 years 7 months ago
In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Tineke Casneuf, Yves Van de Peer, Wolfgang Huber