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BMCBI
2007
94views more  BMCBI 2007»
13 years 8 months ago
Model based analysis of real-time PCR data from DNA binding dye protocols
Background: Reverse transcription followed by real-time PCR is widely used for quantification of specific mRNA, and with the use of double-stranded DNA binding dyes it is becoming...
Mariano J. Alvarez, Guillermo J. Vila-Ortiz, Maria...
BIODATAMINING
2008
96views more  BIODATAMINING 2008»
13 years 9 months ago
Fast approximate hierarchical clustering using similarity heuristics
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Meelis Kull, Jaak Vilo
EVOW
2006
Springer
14 years 15 days ago
Mining Structural Databases: An Evolutionary Multi-Objetive Conceptual Clustering Methodology
Abstract. The increased availability of biological databases containing representations of complex objects permits access to vast amounts of data. In spite of the recent renewed in...
Rocío Romero-Záliz, Cristina Rubio-E...
BMCBI
2010
134views more  BMCBI 2010»
13 years 9 months ago
ScreenMill: A freely available software suite for growth measurement, analysis and visualization of high-throughput screen data
Background: Many high-throughput genomic experiments, such as Synthetic Genetic Array and yeast two-hybrid, use colony growth on solid media as a screen metric. These experiments ...
John C. Dittmar, Robert J. D. Reid, Rodney Rothste...
BMCBI
2010
116views more  BMCBI 2010»
13 years 9 months ago
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
Jeffry D. Sander, Deepak Reyon, Morgan L. Maeder, ...