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» An Efficient Functional Analysis Method for Micro-array Data...
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165
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BMCBI
2008
200views more  BMCBI 2008»
15 years 2 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
137
Voted
AIME
2007
Springer
15 years 9 months ago
Interpreting Gene Expression Data by Searching for Enriched Gene Sets
This paper presents a novel method integrating gene-gene interaction information and Gene Ontology for the construction of new gene sets that are potentially enriched. Enrichment o...
Igor Trajkovski, Nada Lavrac
140
Voted
BMCBI
2007
166views more  BMCBI 2007»
15 years 2 months ago
How to decide which are the most pertinent overly-represented features during gene set enrichment analysis
Background: The search for enriched features has become widely used to characterize a set of genes or proteins. A key aspect of this technique is its ability to identify correlati...
Roland Barriot, David J. Sherman, Isabelle Dutour
129
Voted
BMCBI
2006
169views more  BMCBI 2006»
15 years 2 months ago
Finding biological process modifications in cancer tissues by mining gene expression correlations
Background: Through the use of DNA microarrays it is now possible to obtain quantitative measurements of the expression of thousands of genes from a biological sample. This techno...
Giacomo Gamberoni, Sergio Storari, Stefano Volinia
135
Voted
COMPLIFE
2006
Springer
15 years 6 months ago
Relational Subgroup Discovery for Descriptive Analysis of Microarray Data
Abstract. This paper presents a method that uses gene ontologies, together with the paradigm of relational subgroup discovery, to help find description of groups of genes different...
Igor Trajkovski, Filip Zelezný, Jakub Tolar...