This paper describes an application of IR and text categorization methods to a highly practical problem in biomedicine, specifically, Gene Ontology (GO) annotation. GO annotation...
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
The use of controlled structured vocabularies for annotation purposes, such as the Gene Ontology (GO) is currently one of the strategies to cope with the increasingly cumbersome t...
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Background: Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports...
Andrew S. Warren, Jeremy S. Archuleta, Wu-chun Fen...