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» An Evolutionary Approach for Molecular Docking
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BMCBI
2004
123views more  BMCBI 2004»
13 years 7 months ago
Interaction profile-based protein classification of death domain
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Drew Lett, Michael Hsing, Frederic Pio
LATA
2009
Springer
14 years 2 months ago
From Gene Trees to Species Trees through a Supertree Approach
Abstract. Gene trees are leaf-labeled trees inferred from molecular sequences. Due to duplication events arising in genome evolution, gene trees usually have multiple copies of som...
Celine Scornavacca, Vincent Berry, Vincent Ranwez
JCB
2006
107views more  JCB 2006»
13 years 7 months ago
Maximum Likelihood Molecular Clock Comb: Analytic Solutions
Maximum likelihood (ML) is increasingly used as an optimality criterion for selecting evolutionary trees, but finding the global optimum is a hard computational task. Because no g...
Benny Chor, Amit Khetan, Sagi Snir
BMCBI
2010
131views more  BMCBI 2010»
13 years 2 months ago
Dynamics based alignment of proteins: an alternative approach to quantify dynamic similarity
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
Márton Münz, Rune B. Lyngsø, Jo...
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
13 years 8 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...