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» An Evolutionary Approach for Molecular Docking
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ICASSP
2007
IEEE
14 years 1 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
ISMB
2007
13 years 10 months ago
Automatic genome-wide reconstruction of phylogenetic gene trees
Gene duplication and divergence is a major evolutionary force. Despite the growing number of fully sequenced genomes, methods for investigating these events on a genome-wide scale...
Ilan Wapinski, Avi Pfeffer, Nir Friedman, Aviv Reg...
EVOW
2007
Springer
13 years 11 months ago
Dinucleotide Step Parameterization of Pre-miRNAs Using Multi-objective Evolutionary Algorithms
MicroRNAs (miRNAs) form a large functional family of small noncoding RNAs and play an important role as posttranscriptional regulators, by repressing the translation of mRNAs. Rece...
Jin-Wu Nam, In-Hee Lee, Kyu Baek Hwang, Seong-Bae ...
BMCBI
2010
72views more  BMCBI 2010»
13 years 7 months ago
Phylogenetic representativeness: a new method for evaluating taxon sampling in evolutionary studies
Background: Taxon sampling is a major concern in phylogenetic studies. Incomplete, biased, or improper taxon sampling can lead to misleading results in reconstructing evolutionary...
Federico Plazzi, Ronald R. Ferrucci, Marco Passamo...
BIOCOMP
2006
13 years 9 months ago
An Approach to Selecting Putative RNA Motifs Using MDL Principle
The history of molecular biology is punctuated by a series of discoveries demonstrating the surprising breadth of biological roles of ribonucleic acid (RNA). An ensemble of evoluti...
Mohammad Anwar, Marcel Turcotte