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BMCBI
2010
133views more  BMCBI 2010»
13 years 7 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BMCBI
2007
134views more  BMCBI 2007»
13 years 7 months ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
BMCBI
2006
142views more  BMCBI 2006»
13 years 7 months ago
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
Angela Re, Davide Corà, Alda Maria Puliti, ...
IJES
2006
110views more  IJES 2006»
13 years 7 months ago
Partitioning bin-packing algorithms for distributed real-time systems
Embedded real-time systems must satisfy not only logical functional requirements but also para-functional properties such as timeliness, Quality of Service (QoS) and reliability. W...
Dionisio de Niz, Raj Rajkumar
IPM
2007
143views more  IPM 2007»
13 years 7 months ago
QCS: A system for querying, clustering and summarizing documents
Information retrieval systems consist of many complicated components. Research and development of such systems is often hampered by the difficulty in evaluating how each particula...
Daniel M. Dunlavy, Dianne P. O'Leary, John M. Conr...