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» An Intelligent System for Comparing Protein Structures
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BMCBI
2007
93views more  BMCBI 2007»
13 years 7 months ago
SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
BIOINFORMATICS
2008
97views more  BIOINFORMATICS 2008»
13 years 7 months ago
An integrated system for studying residue coevolution in proteins
Residue coevolution has recently emerged as an important concept, especially in the context of protein structures. While a multitude of different functions for quantifying it have...
Kevin Y. Yip, Prianka Patel, Philip M. Kim, Donald...
RECOMB
2003
Springer
14 years 7 months ago
A multi-expert system for the automatic detection of protein domains from sequence information
We describe a novel method for detecting the domain structure of a protein from sequence information alone. The method is based on analyzing multiple sequence alignments that are ...
Niranjan Nagarajan, Golan Yona
BMCBI
2004
128views more  BMCBI 2004»
13 years 7 months ago
Structural characterization of genomes by large scale sequence-structure threading: application of reliability analysis in struc
Background: We establish that the occurrence of protein folds among genomes can be accurately described with a Weibull function. Systems which exhibit Weibull character can be int...
Artem Cherkasov, Shannan J. Ho Sui, Robert C. Brun...
AI
2003
Springer
14 years 19 days ago
An Improved Ant Colony Optimisation Algorithm for the 2D HP Protein Folding Problem
The prediction of a protein’s structure from its amino-acid sequence is one of the most important problems in computational biology. In the current focus on a widely studied abst...
Alena Shmygelska, Holger H. Hoos