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BMCBI
2006
13 years 7 months ago
2006
Background: Ontologies and taxonomies are among the most important computational resources for molecular biology and bioinformatics. A series of recent papers has shown that the G...
BMCBI
2006
13 years 7 months ago
2006
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
BMCBI
2006
13 years 7 months ago
2006
Background: Microarrays are routinely used to assess mRNA transcript levels on a genome-wide scale. Large amount of microarray datasets are now available in several databases, and...
BMCBI
2006
13 years 7 months ago
2006
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
BMCBI
2006
13 years 7 months ago
2006
Background: The Tissue Microarray (TMA) facilitates high-throughput analysis of hundreds of tissue specimens simultaneously. However, bottlenecks in the storage and manipulation o...