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BMCBI
2010
128views more  BMCBI 2010»
13 years 9 months ago
MPprimer: a program for reliable multiplex PCR primer design
Background: Multiplex PCR, defined as the simultaneous amplification of multiple regions of a DNA template or multiple DNA templates using more than one primer set (comprising a f...
Zhiyong Shen, Wubin Qu, Wen Wang, Yiming Lu, Yongh...
BMCBI
2008
200views more  BMCBI 2008»
13 years 9 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2007
146views more  BMCBI 2007»
13 years 9 months ago
Spatial location and its relevance for terminological inferences in bio-ontologies
Background: An adequate and expressive ontological representation of biological organisms and their parts requires formal reasoning mechanisms for their relations of physical aggr...
Stefan Schulz, Kornél G. Markó, Udo ...
APIN
2006
168views more  APIN 2006»
13 years 9 months ago
Utilizing Genetic Algorithms to Optimize Membership Functions for Fuzzy Weighted Association Rules Mining
It is not an easy task to know a priori the most appropriate fuzzy sets that cover the domains of quantitative attributes for fuzzy association rules mining. In general, it is unre...
Mehmet Kaya, Reda Alhajj
BMCBI
2006
100views more  BMCBI 2006»
13 years 9 months ago
DNPTrapper: an assembly editing tool for finishing and analysis of complex repeat regions
Background: Many genome projects are left unfinished due to complex, repeated regions. Finishing is the most time consuming step in sequencing and current finishing tools are not ...
Erik Arner, Martti T. Tammi, Anh-Nhi Tran, Ellen K...