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» An Open Problem in RNA Secondary Structure Prediction by the...
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BMCBI
2007
165views more  BMCBI 2007»
13 years 7 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
IJCNN
2006
IEEE
14 years 1 months ago
Comparing Kernels for Predicting Protein Binding Sites from Amino Acid Sequence
— The ability to identify protein binding sites and to detect specific amino acid residues that contribute to the specificity and affinity of protein interactions has importan...
Feihong Wu
JCB
2000
146views more  JCB 2000»
13 years 7 months ago
Bayesian Segmentation of Protein Secondary Structure
We present a novel method for predicting the secondary structure of a protein from its amino acid sequence. Most existing methods predict each position in turn based on a local wi...
Scott C. Schmidler, Jun S. Liu, Douglas L. Brutlag
WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
14 years 1 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
BMCBI
2004
138views more  BMCBI 2004»
13 years 7 months ago
Constraint Logic Programming approach to protein structure prediction
Background: The protein structure prediction problem is one of the most challenging problems in biological sciences. Many approaches have been proposed using database information ...
Alessandro Dal Palù, Agostino Dovier, Feder...