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» An Optimal Algorithm for Perfect Phylogeny Haplotyping
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COCOON
2008
Springer
13 years 9 months ago
Haplotype Inferring Via Galled-Tree Networks Is NP-Complete
The problem of determining haplotypes from genotypes has gained considerable prominence in the research community since the beginning of the HapMap project. Here the focus is on de...
Arvind Gupta, Ján Manuch, Ladislav Stacho, ...
RECOMB
2009
Springer
14 years 8 months ago
Haplotype Inference in Complex Pedigrees
Abstract. Despite the desirable information contained in complex pedigree datasets, analysis methods struggle to efficiently process these datasets. The attractiveness of pedigree ...
Bonnie Kirkpatrick, Javier Rosa, Eran Halperin, Ri...
BIOINFORMATICS
2007
90views more  BIOINFORMATICS 2007»
13 years 7 months ago
HAPLOPOOL: improving haplotype frequency estimation through DNA pools and phylogenetic modeling
In the context of disease association studies, haplotype frequencies are usually estimated from genotype data. In order to reduce genotyping costs, one can estimate the haplotype ...
Bonnie Kirkpatrick, Carlos Santos Armendariz, Rich...
BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...