Background: Existing sequence alignment algorithms assume that similarities between DNA or amino acid sequences are linearly ordered. That is, stretches of similar nucleotides or ...
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
The ongoing revolution in life sciences research is producing vast amounts of genetic and proteomic sequence data. Scientists want to pose increasingly complex queries on this dat...
Sandeep Tata, Jignesh M. Patel, James S. Friedman,...
A labeled sequence data set related to a certain biological property is often biased and, therefore, does not completely capture its diversity in nature. To reduce this sampling b...
In this paper we analyze the I/O access patterns of a widely-used biological sequence search tool and implement two variations that employ parallel-I/O for data access based on PV...
Yifeng Zhu, Hong Jiang, Xiao Qin, David R. Swanson