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BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
BMCBI
2007
99views more  BMCBI 2007»
13 years 7 months ago
The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
B. D. Pascal, M. J. Chalmers, S. A. Busby, C. C. M...
TODS
2002
92views more  TODS 2002»
13 years 7 months ago
Searching in metric spaces with user-defined and approximate distances
Metric access methods (MAMs), such as the M-tree, are powerful index structures for supporting ty queries on metric spaces, which represent a common abstraction for those searchin...
Paolo Ciaccia, Marco Patella
CSB
2005
IEEE
210views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Problem Solving Environment Approach to Integrating Diverse Biological Data Sources
Scientists face an ever-increasing challenge in investigating biological systems with high throughput experimental methods such as mass spectrometry and gene arrays because of the...
Eric G. Stephan, Kyle R. Klicker, Mudita Singhal, ...
BMCBI
2007
126views more  BMCBI 2007»
13 years 7 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne