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BMCBI
2006
165views more  BMCBI 2006»
13 years 8 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
BMCBI
2008
142views more  BMCBI 2008»
13 years 8 months ago
Genetic weighted k-means algorithm for clustering large-scale gene expression data
Background: The traditional (unweighted) k-means is one of the most popular clustering methods for analyzing gene expression data. However, it suffers three major shortcomings. It...
Fang-Xiang Wu
SAC
2006
ACM
14 years 1 months ago
Two-phase clustering strategy for gene expression data sets
In the context of genome research, the method of gene expression analysis has been used for several years. Related microarray experiments are conducted all over the world, and con...
Dirk Habich, Thomas Wächter, Wolfgang Lehner,...
BMCBI
2007
134views more  BMCBI 2007»
13 years 8 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
BMCBI
2010
214views more  BMCBI 2010»
13 years 8 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper