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» An association analysis approach to biclustering
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BMCBI
2007
103views more  BMCBI 2007»
13 years 7 months ago
A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Shunpu Zhang
BMCBI
2008
99views more  BMCBI 2008»
13 years 7 months ago
Multiple organism algorithm for finding ultraconserved elements
Background: Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more or...
Scott Christley, Neil F. Lobo, Gregory R. Madey
BMCBI
2006
167views more  BMCBI 2006»
13 years 7 months ago
GOurmet: A tool for quantitative comparison and visualization of gene expression profiles based on gene ontology (GO) distributi
Background: The ever-expanding population of gene expression profiles (EPs) from specified cells and tissues under a variety of experimental conditions is an important but difficu...
Jason M. Doherty, Lynn K. Carmichael, Jason C. Mil...
BMCBI
2006
128views more  BMCBI 2006»
13 years 7 months ago
An interactive tool for visualization of relationships between gene expression profiles
Background: Application of phenetic methods to gene expression analysis proved to be a successful approach. Visualizing the results in a 3-dimentional space may further enhance th...
Peter Ruzanov, Steven J. M. Jones
BMCBI
2007
131views more  BMCBI 2007»
13 years 7 months ago
Prediction of peptides observable by mass spectrometry applied at the experimental set level
Background: When proteins are subjected to proteolytic digestion and analyzed by mass spectrometry using a method such as 2D LC MS/MS, only a portion of the proteotypic peptides a...
William S. Sanders, Susan M. Bridges, Fiona M. McC...