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BMCBI
2010
106views more  BMCBI 2010»
13 years 9 months ago
A novel approach for haplotype-based association analysis using family data
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
Yixuan Chen, Xin Li, Jing Li
BMCBI
2007
174views more  BMCBI 2007»
13 years 9 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
BMCBI
2008
110views more  BMCBI 2008»
13 years 9 months ago
Determining significance of pairwise co-occurrences of events in bursty sequences
Background: Event sequences where different types of events often occur close together arise, e.g., when studying potential transcription factor binding sites (TFBS, events) of ce...
Niina Haiminen, Heikki Mannila, Evimaria Terzi
BMCBI
2008
117views more  BMCBI 2008»
13 years 9 months ago
RNACompress: Grammar-based compression and informational complexity measurement of RNA secondary structure
Background: With the rapid emergence of RNA databases and newly identified non-coding RNAs, an efficient compression algorithm for RNA sequence and structural information is neede...
Qi Liu, Yu Yang, Chun Chen, Jiajun Bu, Yin Zhang, ...
BMCBI
2008
135views more  BMCBI 2008»
13 years 9 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
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