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GECCO
2006
Springer
177views Optimization» more  GECCO 2006»
13 years 11 months ago
Hyper-ellipsoidal conditions in XCS: rotation, linear approximation, and solution structure
The learning classifier system XCS is an iterative rulelearning system that evolves rule structures based on gradient-based prediction and rule quality estimates. Besides classifi...
Martin V. Butz, Pier Luca Lanzi, Stewart W. Wilson
BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
BMCBI
2008
228views more  BMCBI 2008»
13 years 7 months ago
Adaptive diffusion kernel learning from biological networks for protein function prediction
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
Liang Sun, Shuiwang Ji, Jieping Ye
BMCBI
2008
104views more  BMCBI 2008»
13 years 7 months ago
Evolutionary Pareto-optimization of stably folding peptides
Background: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides ...
Wolfram Gronwald, Tim Hohm, Daniel Hoffmann
BMCBI
2007
116views more  BMCBI 2007»
13 years 7 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...