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BMCBI
2007
107views more  BMCBI 2007»
13 years 7 months ago
Linking microarray reporters with protein functions
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
BMCBI
2006
166views more  BMCBI 2006»
13 years 7 months ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto
BMCBI
2007
144views more  BMCBI 2007»
13 years 7 months ago
Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study an
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
Dennis R. Livesay, Patrick D. Kidd, Sepehr Eskanda...
BICOB
2009
Springer
13 years 11 months ago
Constrained Fisher Scores Derived from Interaction Profile Hidden Markov Models Improve Protein to Protein Interaction Predictio
Protein-protein interaction plays critical roles in cellular functions. In this work, we propose a computational method to predict protein-protein interaction by using support vec...
Alvaro J. González, Li Liao
BMCBI
2010
123views more  BMCBI 2010»
13 years 2 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke