167 search results - page 5 / 34 » An improved method for identifying functionally linked prote... |
BMCBI
2010
13 years 7 months ago
2010
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
BMCBI
2005
13 years 7 months ago
2005
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
BMCBI
2007
13 years 7 months ago
2007
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
ALMOB
2006
13 years 7 months ago
2006
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
BMCBI
2006
13 years 7 months ago
2006
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...