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ISDA
2006
IEEE
14 years 1 months ago
From Gene to Drug: A Proof of Concept for a Plausible Computational Pathway
The last decade has witnessed an exponential growth of sequence information in the field of biological macromolecules such as proteins and nucleic acids and their interactions wit...
Sandhya Shenoy, B. Jayaram, N. Latha, Pooja Narang...
BMCBI
2010
97views more  BMCBI 2010»
13 years 7 months ago
Incorporating significant amino acid pairs to identify O-linked glycosylation sites on transmembrane proteins and non-transmembr
Background: While occurring enzymatically in biological systems, O-linked glycosylation affects protein folding, localization and trafficking, protein solubility, antigenicity, bi...
Shu-An Chen, Tzong-Yi Lee, Yu-Yen Ou
BMCBI
2008
153views more  BMCBI 2008»
13 years 7 months ago
Version VI of the ESTree db: an improved tool for peach transcriptome analysis
Background: The ESTree database (db) is a collection of Prunus persica and Prunus dulcis EST sequences that in its current version encompasses 75,404 sequences from 3 almond and 1...
Barbara Lazzari, Andrea Caprera, Alberto Vecchiett...
BMCBI
2007
122views more  BMCBI 2007»
13 years 7 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2007
102views more  BMCBI 2007»
13 years 7 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein