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» Analysis of Large-Scale Sequencing of Small RNAs
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TCS
2008
13 years 7 months ago
A small trip in the untranquil world of genomes: A survey on the detection and analysis of genome rearrangement breakpoints
Genomes are dynamic molecules that are constantly undergoing mutations and rearrangements. The latter are large scale changes in a genome organisation that participate in the evol...
Claire Lemaitre, Marie-France Sagot
BMCBI
2007
113views more  BMCBI 2007»
13 years 7 months ago
miRAS: a data processing system for miRNA expression profiling study
Background: The study of microRNAs (miRNAs) is attracting great considerations. Recent studies revealed that miRNAs play as important regulators of gene expression and some even a...
Feng Tian, Huayue Zhang, Xinyu Zhang, Chi Song, Yo...
BMCBI
2010
129views more  BMCBI 2010»
13 years 7 months ago
Geoseq: a tool for dissecting deep-sequencing datasets
Background: Datasets generated on deep-sequencing platforms have been deposited in various public repositories such as the Gene Expression Omnibus (GEO), Sequence Read Archive (SR...
James Gurtowski, Anthony Cancio, Hardik Shah, Chay...
BMCBI
2006
92views more  BMCBI 2006»
13 years 7 months ago
Demonstration of two novel methods for predicting functional siRNA efficiency
Background: siRNAs are small RNAs that serve as sequence determinants during the gene silencing process called RNA interference (RNAi). It is well know that siRNA efficiency is cr...
Peilin Jia, Tieliu Shi, Yu-Dong Cai, Yixue Li
BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...