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BMCBI
2007
145views more  BMCBI 2007»
13 years 9 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
BMCBI
2010
96views more  BMCBI 2010»
13 years 9 months ago
OpenChrom: a cross-platform open source software for the mass spectrometric analysis of chromatographic data
Background: Today, data evaluation has become a bottleneck in chromatographic science. Analytical instruments equipped with automated samplers yield large amounts of measurement d...
Philip Wenig, Juergen Odermatt
BMCBI
2008
113views more  BMCBI 2008»
13 years 9 months ago
SynBlast: Assisting the analysis of conserved synteny information
Motivation: In the last years more than 20 vertebrate genomes have been sequenced, and the rate at which genomic DNA information becomes available is rapidly accelerating. Gene du...
Jörg Lehmann, Peter F. Stadler, Sonja J. Proh...
BMCBI
2007
79views more  BMCBI 2007»
13 years 9 months ago
Orthology prediction at scalable resolution by phylogenetic tree analysis
Background: Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an ove...
René T. J. M. van der Heijden, Berend Snel,...
EOR
2008
123views more  EOR 2008»
13 years 9 months ago
A combined approach for segment-specific market basket analysis
Market baskets arise from consumers' shopping trips and include items from multiple categories that are frequently chosen interdependently from each other. Explanatory models...
Yasemin Boztug, Thomas Reutterer