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» Analysis of Protein Protein Dimeric Interfaces
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BMCBI
2005
95views more  BMCBI 2005»
13 years 7 months ago
Oligomeric protein structure networks: insights into protein-protein interactions
Background: Protein-protein association is essential for a variety of cellular processes and hence a large number of investigations are being carried out to understand the princip...
K. V. Brinda, Saraswathi Vishveshwara
BMCBI
2010
128views more  BMCBI 2010»
13 years 7 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2005
125views more  BMCBI 2005»
13 years 7 months ago
Query3d: a new method for high-throughput analysis of functional residues in protein structures
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...
Gabriele Ausiello, Allegra Via, Manuela Helmer-Cit...
BMCBI
2006
129views more  BMCBI 2006»
13 years 7 months ago
BIPAD: A web server for modeling bipartite sequence elements
Background: Many dimeric protein complexes bind cooperatively to families of bipartite nucleic acid sequence elements, which consist of pairs of conserved half-site sequences sepa...
Chengpeng Bi, Peter K. Rogan