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BMCBI
2010
176views more  BMCBI 2010»
13 years 4 months ago
Haplotype association analyses in resources of mixed structure using Monte Carlo testing
Background: Genomewide association studies have resulted in a great many genomic regions that are likely to harbor disease genes. Thorough interrogation of these specific regions ...
Ryan Abo, Jathine Wong, Alun Thomas, Nicola J. Cam...
BMCBI
2008
111views more  BMCBI 2008»
13 years 7 months ago
SimHap GUI: An intuitive graphical user interface for genetic association analysis
Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-f...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
EUROGP
2005
Springer
107views Optimization» more  EUROGP 2005»
14 years 28 days ago
Operator-Based Distance for Genetic Programming: Subtree Crossover Distance
Abstract. This paper explores distance measures based on genetic operators for genetic programming using tree structures. The consistency between genetic operators and distance mea...
Steven M. Gustafson, Leonardo Vanneschi
ISBI
2011
IEEE
12 years 11 months ago
Hierarchical clustering of the genetic connectivity matrix reveals the network topology of gene action on brain microstructure:
Genetic correlation (rg) analysis determines how much of the correlation between two measures is due to common genetic influences. In an analysis of 4 Tesla diffusion tensor image...
Ming-Chang Chiang, Marina Barysheva, Katie McMahon...
BMCBI
2010
62views more  BMCBI 2010»
13 years 7 months ago
Forward-time simulation of realistic samples for genome-wide association studies
Background: Forward-time simulations have unique advantages in power and flexibility for the simulation of genetic samples of complex human diseases because they can closely mimic...
Bo Peng, Christopher I. Amos