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ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
13 years 7 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki
GEOINFORMATICA
2007
223views more  GEOINFORMATICA 2007»
13 years 7 months ago
Algorithms for Nearest Neighbor Search on Moving Object Trajectories
Nearest Neighbor (NN) search has been in the core of spatial and spatiotemporal database research during the last decade. The literature on NN query processing algorithms so far d...
Elias Frentzos, Kostas Gratsias, Nikos Pelekis, Ya...
CODES
2008
IEEE
14 years 2 months ago
Static analysis for fast and accurate design space exploration of caches
Application-specific system-on-chip platforms create the opportunity to customize the cache configuration for optimal performance with minimal chip estate. Simulation, in partic...
Yun Liang, Tulika Mitra
GCB
2009
Springer
180views Biometrics» more  GCB 2009»
14 years 2 months ago
2D Projections of RNA Folding Landscapes
Abstract: The analysis of RNA folding landscapes yields insights into the kinetic folding behavior not available from classical structure prediction methods. This is especially imp...
Ronny Lorenz, Christoph Flamm, Ivo L. Hofacker
BMCBI
2007
148views more  BMCBI 2007»
13 years 7 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...