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BMCBI
2007
124views more  BMCBI 2007»
13 years 7 months ago
Analysis on multi-domain cooperation for predicting protein-protein interactions
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
Rui-Sheng Wang, Yong Wang, Ling-Yun Wu, Xiang-Sun ...
CSB
2003
IEEE
176views Bioinformatics» more  CSB 2003»
14 years 28 days ago
3D Structural Homology Detection via Unassigned Residual Dipolar Couplings
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
Christopher James Langmead, Bruce Randall Donald
BMCBI
2010
110views more  BMCBI 2010»
13 years 6 months ago
Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
Miguel A. Anton, Ander Aramburu, Angel Rubio
TCBB
2010
104views more  TCBB 2010»
13 years 6 months ago
Fast Hinge Detection Algorithms for Flexible Protein Structures
— Analysis of conformational changes is one of the keys to the understanding of protein functions and interactions. For the analysis, we often compare two protein structures, tak...
Tetsuo Shibuya
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
MOTIPS: Automated Motif Analysis for Predicting Targets of Modular Protein Domains
Background: Many protein interactions, especially those involved in signaling, involve short linear motifs consisting of 5-10 amino acid residues that interact with modular protei...
Hugo Y. K. Lam, Philip M. Kim, Janine Mok, Raffi T...