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BMCBI
2011
13 years 2 months ago
Logical Development of the Cell Ontology
Background: The Cell Ontology (CL) is an ontology for the representation of in vivo cell types. As biological ontologies such as the CL grow in complexity, they become increasingl...
Terrence F. Meehan, Anna Maria Masci, Amina Abdull...
BMCBI
2010
150views more  BMCBI 2010»
13 years 7 months ago
DeltaProt: a software toolbox for comparative genomics
Background: Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding o...
Steinar Thorvaldsen, Tor Flå, Nils Willassen
NAR
2008
107views more  NAR 2008»
13 years 7 months ago
MutDB: update on development of tools for the biochemical analysis of genetic variation
Understanding how genetic variation affects the molecular function of gene products is an emergent area of bioinformatic research. Here, we present updates to MutDB (http://www.mu...
Arti Singh, Adebayo Olowoyeye, Peter H. Baenziger,...
BMCBI
2007
102views more  BMCBI 2007»
13 years 7 months ago
Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms
Background: The number of algorithms available to predict ligand-protein interactions is large and ever-increasing. The number of test cases used to validate these methods is usua...
Luis A. Diago, Persy Morell, Longendri Aguilera, E...
BMCBI
2010
113views more  BMCBI 2010»
13 years 7 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...