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BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
ICML
2005
IEEE
14 years 8 months ago
Ensembles of biased classifiers
We propose a novel ensemble learning algorithm called Triskel, which has two interesting features. First, Triskel learns an ensemble of classifiers, each biased to have high preci...
Andreas Heß, Nicholas Kushmerick, Rinat Khou...
ICDE
2010
IEEE
199views Database» more  ICDE 2010»
14 years 2 months ago
Mining mutation chains in biological sequences
— The increasing infectious disease outbreaks has led to a need for new research to better understand the disease’s origins, epidemiological features and pathogenicity caused b...
Chang Sheng, Wynne Hsu, Mong-Li Lee, Joo Chuan Ton...
BMCBI
2007
114views more  BMCBI 2007»
13 years 7 months ago
Gene models from ESTs (GeneModelEST): an application on the Solanum lycopersicum genome
Background: The structure annotation of a genome is based either on ab initio methodologies or on similaritiy searches versus molecules that have been already annotated. Ab initio...
Nunzio D'Agostino, Alessandra Traini, Luigi Frusci...
EDBT
2012
ACM
257views Database» more  EDBT 2012»
11 years 10 months ago
Indexing and mining topological patterns for drug discovery
Increased availability of large repositories of chemical compounds has created new challenges and opportunities for the application of data-mining and indexing techniques to probl...
Sayan Ranu, Ambuj K. Singh