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BMCBI
2010
115views more  BMCBI 2010»
13 years 9 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2007
112views more  BMCBI 2007»
13 years 9 months ago
PFAAT version 2.0: A tool for editing, annotating, and analyzing multiple sequence alignments
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...
BMCBI
2010
128views more  BMCBI 2010»
13 years 9 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
SIGIR
2008
ACM
13 years 8 months ago
On profiling blogs with representative entries
With an explosive growth of blogs, information seeking in blogosphere becomes more and more challenging. One example task is to find the most relevant topical blogs against a give...
Jinfeng Zhuang, Steven C. H. Hoi, Aixin Sun
ISBI
2007
IEEE
14 years 3 months ago
Automatic Segmentation of Nuclei in 3d Microscopy Images of C.Elegans
Automatic segmentation of nuclei in 3D microscopy images is essential for many biological studies including high throughput analysis of gene expression level, morphology, and phen...
Fuhui Long, Hanchuan Peng, Eugene W. Myers