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BMCBI
2007
13 years 8 months ago
2007
Background: The underlying goal of microarray experiments is to identify gene expression patterns across different experimental conditions. Genes that are contained in a particula...
BMCBI
2008
13 years 8 months ago
2008
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
BMCBI
2010
13 years 8 months ago
2010
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
BMCBI
2007
13 years 8 months ago
2007
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
BMCBI
2010
13 years 8 months ago
2010
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...