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BMCBI
2007
103views more  BMCBI 2007»
13 years 8 months ago
A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Shunpu Zhang
BMCBI
2007
106views more  BMCBI 2007»
13 years 8 months ago
Modeling SAGE tag formation and its effects on data interpretation within a Bayesian framework
Background: Serial Analysis of Gene Expression (SAGE) is a high-throughput method for inferring mRNA expression levels from the experimentally generated sequence based tags. Stand...
Michael A. Gilchrist, Hong Qin, Russell L. Zaretzk...
BMCBI
2008
126views more  BMCBI 2008»
13 years 8 months ago
Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution
Background: In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. Howe...
Stefano Moretti, Danitsja van Leeuwen, Hans Gmuend...
PROMISE
2010
13 years 3 months ago
The role of the measure of functional complexity in effort estimation
Background. Currently there are several definitions of measures that should represent the size of software functional requirements. These measures have gained a quite relevant rol...
Luigi Lavazza, Gabriela Robiolo
BMCBI
2006
109views more  BMCBI 2006»
13 years 8 months ago
HaploRec: efficient and accurate large-scale reconstruction of haplotypes
Background: Haplotypes extracted from human DNA can be used for gene mapping and other analysis of genetic patterns within and across populations. A fundamental problem is, howeve...
Lauri Eronen, Floris Geerts, Hannu Toivonen