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BMCBI
2006
94views more  BMCBI 2006»
15 years 4 months ago
Simulation of microarray data with realistic characteristics
Background: Microarray technologies have become common tools in biological research. As a result, a need for effective computational methods for data analysis has emerged. Numerou...
Matti Nykter, Tommi Aho, Miika Ahdesmäki, Pek...
BMCBI
2008
132views more  BMCBI 2008»
15 years 4 months ago
Mixture models for analysis of melting temperature data
Background: In addition to their use in detecting undesired real-time PCR products, melting temperatures are useful for detecting variations in the desired target sequences. Metho...
Christoffer Nellåker, Fredrik Uhrzander, Joa...
BMCBI
2007
150views more  BMCBI 2007»
15 years 4 months ago
Refining intra-protein contact prediction by graph analysis
Background: Accurate prediction of intra-protein residue contacts from sequence information will allow the prediction of protein structures. Basic predictions of such specific con...
Milana Frenkel-Morgenstern, Rachel Magid, Eran Eya...
PROMISE
2010
14 years 11 months ago
Defect cost flow model: a Bayesian network for predicting defect correction effort
Background. Software defect prediction has been one of the central topics of software engineering. Predicted defect counts have been used mainly to assess software quality and est...
Thomas Schulz, Lukasz Radlinski, Thomas Gorges, Wo...
BMCBI
2010
130views more  BMCBI 2010»
15 years 4 months ago
Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
Karel Zimmermann, Jean-François Gibrat