Biomodel engineering is the science of designing, constructing and analyzing computational models of biological systems. It forms a systematic and powerful extension of earlier mat...
Rainer Breitling, Robin Donaldson, David R. Gilber...
The aim of the paper is to revisit the model of Biological Regulatory Networks (BRN) which was proposed by René Thomas to model the interactions between a set of genes. We give a...
Background: The biological information in genomic expression data can be understood, and computationally extracted, in the context of systems of interacting molecules. The automat...
Bruz Marzolf, Eric W. Deutsch, Patrick Moss, David...
Models will play a central role in the representation, storage, manipulation, and communication of knowledge in systems biology. Models capable of fulfilling such a role will like...
Many years of experimental and computational molecular biology of model organisms such as Escherichia coli and Saccharomyces cerevisiae has elucidated the gene regulatory network i...