Abstract. An important problem in the bioinformatics field is to understand how genes are regulated and interact through gene networks. This knowledge can be helpful for many appl...
Microarray experiments are emerging as one of the main driving forces in modern biology. By allowing the simultaneous monitoring of the expression of the entire genome for a given...
With increasing interest in bioinformatics, sophisticated tools are required to efficiently analyze gene information. The classification of gene expression profiles is crucial in ...
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
Background: When analyzing microarray gene expression data, missing values are often encountered. Most multivariate statistical methods proposed for microarray data analysis canno...