Discrete temporal transitions occur in a variety of domains, but this work is mainly motivated by applications in molecular biology: explaining and analyzing observed transcriptome...
Background: Both microarrays and quantitative real-time PCR are convenient tools for studying the transcriptional levels of genes. The former is preferable for large scale studies...
Andreas W. Schreiber, Neil J. Shirley, Rachel A. B...
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
The Laminin(LM)-database, hosted at http://www .lm.lncc.br, is the first database focusing a noncollagenous extracellular matrix protein family, the LMs. Part of the knowledge ava...
Daiane C. F. Golbert, Leandra Linhares-Lacerda, Lu...
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...