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BMCBI
2006
132views more  BMCBI 2006»
15 years 4 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas
BMCBI
2007
78views more  BMCBI 2007»
15 years 4 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
BMCBI
2007
165views more  BMCBI 2007»
15 years 4 months ago
Automatic reconstruction of a bacterial regulatory network using Natural Language Processing
Background: Manual curation of biological databases, an expensive and labor-intensive process, is essential for high quality integrated data. In this paper we report the implement...
Carlos Rodríguez Penagos, Heladia Salgado, ...
BMCBI
2007
102views more  BMCBI 2007»
15 years 4 months ago
A mixture of feature experts approach for protein-protein interaction prediction
High-throughput methods can directly detect the set of interacting proteins in yeast but the results are often incomplete and exhibit high false positive and false negative rates....
Yanjun Qi, Judith Klein-Seetharaman, Ziv Bar-Josep...
BMCBI
2007
174views more  BMCBI 2007»
15 years 4 months ago
ESTuber db: an online database for Tuber borchii EST sequences
Background: The ESTuber database (http://www.itb.cnr.it/estuber) includes 3,271 Tuber borchii expressed sequence tags (EST). The dataset consists of 2,389 sequences from an in-hou...
Barbara Lazzari, Andrea Caprera, Cristian Cosentin...
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