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BMCBI
2010
179views more  BMCBI 2010»
13 years 7 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BMCBI
2010
100views more  BMCBI 2010»
13 years 7 months ago
Partitioning of copy-number genotypes in pedigrees
Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
Louis-Philippe Lemieux Perreault, Gregor U. Andelf...
BMCBI
2010
202views more  BMCBI 2010»
13 years 7 months ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader
BMCBI
2007
154views more  BMCBI 2007»
13 years 7 months ago
Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms
Background: Identifying syntenic regions, i.e., blocks of genes or other markers with evolutionary conserved order, and quantifying evolutionary relatedness between genomes in ter...
Amit U. Sinha, Jaroslaw Meller
BMCBI
2010
178views more  BMCBI 2010»
13 years 7 months ago
Applications of a formal approach to decipher discrete genetic networks
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
Fabien Corblin, Eric Fanchon, Laurent Trilling
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