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BMCBI
2010
13 years 9 months ago
2010
Background: Primer and probe sequences are the main components of nucleic acid-based detection systems. Biologists use primers and probes for different tasks, some related to the ...
BMCBI
2007
13 years 9 months ago
2007
Background: Sequence motifs representing transcription factor binding sites (TFBS) are commonly encoded as position frequency matrices (PFM) or degenerate consensus sequences (CS)...
BMCBI
2007
13 years 9 months ago
2007
Background: Large molecular sequence databases are fundamental resources for modern bioscientists. Whether for project-specific purposes or sharing data with colleagues, it is oft...
BMCBI
2008
13 years 9 months ago
2008
Background: At intermediate stages of genome assembly projects, when a number of contigs have been generated and their validity needs to be verified, it is desirable to align thes...
BMCBI
2008
13 years 9 months ago
2008
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packa...