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BMCBI
2008
142views more  BMCBI 2008»
13 years 7 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
BMCBI
2008
102views more  BMCBI 2008»
13 years 7 months ago
Ornithine decarboxylase antizyme finder (OAF): Fast and reliable detection of antizymes with frameshifts in mRNAs
Background: Ornithine decarboxylase antizymes are proteins which negatively regulate cellular polyamine levels via their affects on polyamine synthesis and cellular uptake. In vir...
Michaël Bekaert, Ivaylo P. Ivanov, John F. At...
BMCBI
2008
78views more  BMCBI 2008»
13 years 7 months ago
Genome Environment Browser (GEB): a dynamic browser for visualising high-throughput experimental data in the context of genome f
Background: There is accumulating evidence that the milieu of repeat elements and other nongenic sequence features at a given chromosomal locus, here defined as the genome environ...
Derek Huntley, Y. Amy Tang, Tatyana B. Nesterova, ...
BMCBI
2008
125views more  BMCBI 2008»
13 years 7 months ago
SNPLims: a data management system for genome wide association studies
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
Alessandro Orro, Guia Guffanti, Erika Salvi, Fabio...
ALMOB
2006
155views more  ALMOB 2006»
13 years 7 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg