Motivation: In the last years more than 20 vertebrate genomes have been sequenced, and the rate at which genomic DNA information becomes available is rapidly accelerating. Gene du...
Background: Single-pass, partial sequencing of complementary DNA (cDNA) libraries generates thousands of chromatograms that are processed into high quality expressed sequence tags...
Charu G. Kumar, Richard LeDuc, George Gong, Levan ...
Background: High-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to a...
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Background: There is accumulating evidence that the milieu of repeat elements and other nongenic sequence features at a given chromosomal locus, here defined as the genome environ...
Derek Huntley, Y. Amy Tang, Tatyana B. Nesterova, ...