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BMCBI
2007
197views more  BMCBI 2007»
13 years 10 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
BMCBI
2008
170views more  BMCBI 2008»
13 years 10 months ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini
BMCBI
2008
124views more  BMCBI 2008»
13 years 10 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BMCBI
2008
211views more  BMCBI 2008»
13 years 10 months ago
CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment
Background: Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more t...
Svetlin Manavski, Giorgio Valle
CERA
2010
105views more  CERA 2010»
13 years 10 months ago
Implications of Alternative Multilevel Design Methods for Design Process Management
Multilevel design problems are typically decomposed into a hierarchy of distributed and strongly coupled sub-problems, each solved by design teams with specialized knowledge and t...
David Shahan, Carolyn Seepersad Seepersad
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