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BMCBI
2008
133views more  BMCBI 2008»
13 years 10 months ago
SPIKE - a database, visualization and analysis tool of cellular signaling pathways
Background: Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are ...
Ran Elkon, Rita Vesterman, Nira Amit, Igor Ulitsky...
BMCBI
2007
134views more  BMCBI 2007»
13 years 10 months ago
A framework for significance analysis of gene expression data using dimension reduction methods
Background: The most popular methods for significance analysis on microarray data are well suited to find genes differentially expressed across predefined categories. However, ide...
Lars Halvor Gidskehaug, Endre Anderssen, Arnar Fla...
BMCBI
2010
154views more  BMCBI 2010»
13 years 10 months ago
Candidate gene prioritization by network analysis of differential expression using machine learning approaches
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Daniela Nitsch, Joana P. Gonçalves, Fabian ...
BMCBI
2008
154views more  BMCBI 2008»
13 years 10 months ago
GenomeMatcher: A graphical user interface for DNA sequence comparison
Background: The number of available genome sequences is increasing, and easy-to-use software that enables efficient comparative analysis is needed. Results: We developed GenomeMat...
Yoshiyuki Ohtsubo, Wakako Ikeda-Ohtsubo, Yuji Naga...
BMCBI
2007
125views more  BMCBI 2007»
13 years 10 months ago
Bayesian meta-analysis models for microarray data: a comparative study
Background: With the growing abundance of microarray data, statistical methods are increasingly needed to integrate results across studies. Two common approaches for meta-analysis...
Erin M. Conlon, Joon J. Song, Anna Liu