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AI
2003
Springer
14 years 7 days ago
An Improved Ant Colony Optimisation Algorithm for the 2D HP Protein Folding Problem
The prediction of a protein’s structure from its amino-acid sequence is one of the most important problems in computational biology. In the current focus on a widely studied abst...
Alena Shmygelska, Holger H. Hoos
CEC
2009
IEEE
13 years 11 months ago
A parallel genetic algorithm for protein folding prediction using the 3D-HP Side Chain model
— This work presents a methodology for the application of a parallel genetic algorithm (PGA) to the problem of protein folding prediction, using the 3DHP-Side Chain model. This m...
César Manuel Vargas Benítez, Heitor ...
BMCBI
2008
104views more  BMCBI 2008»
13 years 7 months ago
Evolutionary Pareto-optimization of stably folding peptides
Background: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides ...
Wolfram Gronwald, Tim Hohm, Daniel Hoffmann
RECOMB
2009
Springer
14 years 7 months ago
Simultaneous Alignment and Folding of Protein Sequences
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Bonnie Berger, Charles W. O'Donnell, Jér&oc...
BMCBI
2010
189views more  BMCBI 2010»
13 years 7 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...