The prediction of a protein’s structure from its amino-acid sequence is one of the most important problems in computational biology. In the current focus on a widely studied abst...
— This work presents a methodology for the application of a parallel genetic algorithm (PGA) to the problem of protein folding prediction, using the 3DHP-Side Chain model. This m...
Background: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides ...
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...