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BMCBI
2007
89views more  BMCBI 2007»
13 years 7 months ago
msmsEval: tandem mass spectral quality assignment for high-throughput proteomics
Background: In proteomics experiments, database-search programs are the method of choice for protein identification from tandem mass spectra. As amino acid sequence databases grow...
Jason W. H. Wong, Matthew J. Sullivan, Hugh M. Car...
BMCBI
2008
115views more  BMCBI 2008»
13 years 7 months ago
Systems biology driven software design for the research enterprise
Background: In systems biology, and many other areas of research, there is a need for the interoperability of tools and data sources that were not originally designed to be integr...
John Boyle, Christopher C. Cavnor, Sarah A. Killco...
BMCBI
2008
117views more  BMCBI 2008»
13 years 7 months ago
Using a logical model to predict the growth of yeast
Background: A logical model of the known metabolic processes in S. cerevisiae was constructed from iFF708, an existing Flux Balance Analysis (FBA) model, and augmented with inform...
Ken E. Whelan, Ross D. King
BMCBI
2010
88views more  BMCBI 2010»
13 years 7 months ago
Proteome scanning to predict PDZ domain interactions using support vector machines
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Shirley Hui, Gary D. Bader
BMCBI
2007
99views more  BMCBI 2007»
13 years 7 months ago
Stratification bias in low signal microarray studies
Background: When analysing microarray and other small sample size biological datasets, care is needed to avoid various biases. We analyse a form of bias, stratification bias, that...
Brian J. Parker, Simon Günter, Justin Bedo
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